CBG: The Overlooked “Mother” of Cannabinoids

CBG, Cannabigerol, is referred to as the mother of all cannabinoids because all cannabinoids such as CBD and THC are created by the cannabis plant from this very first compound. Research has shown that CBG binds primally with CB2 receptors in our, and mildly with CB1 receptors, which are part of our bodies natural endocannabinoid system. CB1 receptors are primarily found in the brain and central nervous system, while CB2 receptors are in the peripheral organs and in cells associated with the immune system. When CBG binds with these receptors, it provides the anti-inflammatory effect on a cellular level, which provides us relief!

CBG is also a possible inhibitor to the psychoactive properties of THC. CBG is thought to boost anandamide, which is the cannabinoid our bodies produce naturally. CBG, like many of the other cannabinoids, touts its own benefits for health and wellness.

As a cancer fighting agent, CBG was shown to block receptors that cause cancer cell growth, and in one such study, CBG was shown to prevent growth of colorectal cancer cells. 

Endocannabinoid receptors are prevalent in the eye structures, and CBG is thought to be particularity effective in treating glaucoma as it reduces intraocular pressure. More research regarding the eye structure is needed to know exactly how CBG may aid this system.

In a 2015 study, CBG was shown to protect neurons which could slow down the progression of Huntington’s disease, which is characterized by nerve cell degeneration in the brain. European researched revealed evidence that CBG has effective antibacterial properties, especially against MRSA which is resistant to conventional antibiotic treatments.

Since marijuana contains low concentrations of CBG, it is difficult to find a particular strain that, when smoked, can produce the same effects of an extract. Extracts provide a quick and easy way to deliver CBG to the body.

As more research is conducted on the health benefits of CBG, alone or coupled with other cannabinoids, we are hopeful that more medicinal uses will be revealed!